Protein Details: Pannexin-3

Protein ID

ICDB_Pro_1406

Protein Name

Pannexin-3

Gene Name

PANX3

Organism

Homo sapiens (Human)

Length

392 amino acids

AlphaFoldDB

AF-Q96QZ0-F1-model_v4.pdb

Function

Structural component of the gap junctions and the hemichannels.

Sequence

MSLAHTAAEYMLSDALLPDRRGPRLKGLRLELPLDRIVKFVAVGSPLLLMSLAFAQEFSSGSPISCFSPSNFSIRQAAYVDSSCWDSLLHHKQDGPGQDKMKSLWPHKALPYSLLALALLMYLPVLLWQYAAVPALSSDLLFIISELDKSYNRSIRLVQHMLKIRQKSSDPYVFWNELEKARKERYFEFPLLERYLACKQRSHSLVATYLLRNSLLLIFTSATYLYLGHFHLDVFFQEEFSCSIKTGLLSDETHVPNLITCRLTSLSIFQIVSLSSVAIYTILVPVIIYNLTRLCRWDKRLLSVYEMLPAFDLLSRKMLGCPINDLNVILLFLRANISELISFSWLSVLCVLKDTTTQKHNIDTVVDFMTLLAGLEPSKPKHLTNSACDEHP

PDB Structures

7XL6

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Ohdo Syndrome;Sbbys Variant and Ohdo Syndrome

Location

DOI ID

RefSeq

NP_443191.1